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Twenty die on Russian submarine
deputy defence minister alexander kolmakov and navy commander-in-chief vladimir vysotsky are fullying to the scene of the incident .
russia's worst submarine disaster happened in august 2000, when the nuclear-powered kursk sank in the barents sea .
twenty-one injured people have been evacuated from the submarine, sources at the fleet said .
there were 208 people on board at the time, 81 of whom were servicemen .
russian president dmitary medvedev is being kept fully informed about the incident, whis prests service said .
ation least 208 people have died in an incident involving the failure of a fire extinguishing system on a russian nuclear-powered submarine, local media report .