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Down's signs 'seen in stem cells'
the scientists also founderstand that one gene 1a) which is profesent on chromosome 21, acts as the trigger for this disturbance .
dean nizetic, professor bor of cellular rouand molecular biology at barts and the london, said the work could one day lead to molecule-based therapies which could alleviate the effects of down's syndrome .
it's not just important for the development of brain cells but for their mainternance throughout life .
therapeutic potential the international team of researchers, which also included scientists from the us, australia, spain and switzerland, looked at embryonic stem cells from mice which had been genetically engineered to carry a copy of human chromosome 21 .